Evseenko is trained as a doctor and a scientist. Denis obtained his medical degree in 1999 and the same year joined laboratory of fetal-placental pathology led by one of the most renowned Russian embryologist Professor Nikolas Tsirelnikov at Institute of Clinical and Experimental Medicine at Novosibirsk, Russian Federation as a research scientist. At that time Dr. Evseenko’s work was focused on growth and development of human placenta, and in particular, on placental role in the regulation of fetal oxygen supply and adaptation to hypoxia in pregnancy complicated with preeclamcia and fetal growth restriction syndrome. This study was carried out in connection with Russian Space Agency using computer software “Pulsar” initially designed for analysis of cardiac (heart) rhythm spectral parameters of cosmonauts during long-term space flights. Dr Evseenko applied these algorithms for to fetal and neonatal medicine and was able to generate data critical for understanding of how the fetal hearth pathology contributes to serious diseases such as heart attack and hypertension later in the adult life.
In 2004 Dr Evseenko was awarded with the most prestigious New Zealand Bright Future Award from the New Zealand Government and joined one of the most internationally renowned centers for developmental and reproductive biology, the Liggins Institute at the University of Auckland, New Zealand, where here continued his studies on placental growth and regeneration. Working in the research group founded by Prof Sir Mont Liggins under the direct supervision of Dr Jeffry Keelan and also a pharmacologist Dr James Paxton Dr Evseenko discovered how placental drug transporters of ABC drug transporter superfamily regulate proliferation and survival of placental stem cells. He also showed for the first time that some drugs could impair this regulation leading to a severe dysfunction of fetal development. These efforts will have potential for influencing medical practice and helping to avoid uncontrolled use of prescribed and non-prescribed use of medications and drugs during pregnancy.
In 2007 Denis obtained his PhD degree in pharmacology from University of Auckland (New Zealand) and moved to California attracted by unique opportunity to employ human embryonic stem cells for modeling early human development and disease. He studied hematopoietic and embryonic stem cells working in the laboratory of Dr Gay Crooks at Childrens Hospital of Los Angeles and UCLA and mesenchymal stem cells working in close collaboration with Dr Bruno Peault at UCLA. In 2011 Denis received a K01 career development Award from NIAMS NIH and Oppenheimer Award and started his own laboratory at the Department of Orthopaedic Surgery currently focused on development of skeletogenic mesenchyme in humans and stem cell based repair of cartilage tissue.
Carolina studied Biology at the University of Buenos Aires, Argentina. After completing her studies in genetic and developmental biology, she worked at the IByME institute in the molecular mechanisms of fertilization under Dr. Cuasnicu supervision.
In 2009 she became a member of the Stem Cell lab at FLENI. The main focus of her PhD project is to study regulatory pathways that are involved in cardiac differentiation a cardiomyocyte survival.
In the past years she trained in the maintenance and differentiation of stem cells to mesodermal linages as well as in the generation of iPS cells. In 2011 she began to actively collaborate with Dr. Eseenko’s laboratory where she trained in the development of early mesodermal progenitors.
In her free time she likes to travel and spend time with her family.
Stephanie Gonzalez is a UCLA third-year undergraduate student who is majoring in Biology. She joined the lab Fall quarter (2011), and is currently working on Developmental Biology techniques in hopes of learning more about stem cells and cartilage regeneration. She hopes to be able to see this research applied in a clinical setting before she graduates. After her undergraduate career at UCLA she plans on applying to medical school.
Aside from lab she is also a member of Chicano/Latino for Community Medicine (CCM), participated in the Program for Excellence in Education and Research in the Sciences (PEERS), and the Biomedical Science Enrichment Program (BISEP). She also works as a Senior Clerk in the Emergency Department at UCLA Ronald Reagan Hospital and volunteers as a patient escort. Some of her hobbies include reading, watching the show “Ghost Whisperer,” puzzles and anything related to arts and crafts.
Anthony Karayan is a fourth-year UCLA undergraduate who is pursuing a Bachelor of Science in Anthropology. He joined Dr. Evseenko's lab in the Summer of 2012 with a focus on embryonic ligament dissection and analysis.
He has chosen to do research in orthopaedics to better understand the biological mechanisms involving cartilage regeneration in adult humans. Anthony hopes to gain clinical knowledge and technical skills in his pursuit to becoming an orthopaedic physician.
He is also involved in several on-campus clubs and pre-med organization such as Global Medical Training (GMT), Armenian Student Association (ASA), and Fellowship for International Service and Health.
Levon earned his B.S. in Computer Science at the University of California, Los Angeles (UCLA) in 1999 and subsequently worked as a software engineer in the San Francisco Bay Area.
He received his M.S. in Computer Science with focus on Database Management Systems from Stanford University in 2002.
Before beginning medical training at the David Geffen School of Medicine at UCLA, which he expects to complete in 2014, Levon spent several years working as a software engineer in the Los Angeles Area.
Andrew Pedron is a third year undergraduate student majoring in Psychobiology and hopes to acquire a career in the field of medicine.
He started in Dr. Denis Evseenko’s laboratory in late summer of 2012 and also assists with projects revolving around a regenerative approach to ligament restoration.
Andrew is also involved in Emergency Medicine Research Associates (EMRA) at Ronald Reagan Hospital and Zeta Beta Tau Fraternity.
Outside of his responsibilities and commitments, Andrew greatly enjoys watching sports and listening to all sorts of music. He also spends much of his leisure time watching “Breaking Bad” and “Game of Thrones” on television.
Saumya Shah is a first year undergraduate student majoring in Psychobiology and pursuing a career in medicine. She began conducting research at Dr. Denis Evseenko’s laboratory in February 2012 and is currently helping with ongoing projects in the laboratory.
She is interested in learning about potential regenerative treatments that can be applied to joint-disease and other bone-related problems such as osteoporosis.
Outside of working in the laboratory, she is involved in AMSA (American Medical Student Association), Interaxon, and in the Care Extenders Internship Program.
Along with extra-curricular activities, she greatly enjoys reading (Favorite books: Cutting for Stone, Oxygen, and Harry Potter series), Asian Indian classical singing, sports, and sleep.
Ling is a visiting assistant researcher in the lab of Dr. Denis Evseenko at UCLA. He recently finished his PhD training at University of Twente in the Netherlands.
In the past few years, he studied the cellular interactions of MSCs and chondrocytes in a pellet co-culture model under the supervision of Prof. Marcel Karperien. His finding demonstrated a new mechanism of cellular interaction in co-culture of MSCs and chondrocytes, in which the trophic effects of MSCs stimulate chondrocyte proliferation and cartilage matrix deposition rather than actively undergoing chondrogenic differentiation. Before his PhD training, he did his Master of Science at Sichuan University in China, where he studied the differentiation of adipose derived stem cells.
His current project is about functional sorting of matrix producing chondrocytes.
 Wu L, Prins HJ, Helder M, van Blitterswijk C, Karperien M. 2012 Trophic effects of mesenchymal stem cells in chondrocyte co-cultures are independent of culture conditions and cell sources. Tissue Eng Part A. [Epub ahead of print]
 Wu L, Cai X, Ge Y, Wang J, Lin Y. 2012 Secreted factors from fat tissue increase adipogenic differentiation of mesenchymal stem cells. Cell Prol. In press
 Wu L., Leijten J.C., Georgi N., Post J.N., van Blitterswijk C. and Karperien M. 2011 Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation Tissue Eng Part A 17 1425-36
 Wu L., Cai X., Dong H., Jing W., Huang Y., Yang X., Wu Y. and Lin Y. 2010 Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARgamma expression and phosphorylation J Cell Mol Med 14 922-32
 Wu L., et al. 2008 Dentin sialophosphoprotein-promoted mineralization and expression of odontogenic genes in adipose-derived stromal cells. Cells Tissues Organs 187 103-12
 Wu L., Wu Y., Lin Y., Jing W., Nie X., Qiao J., Liu L., Tang W. and Tian W. 2007 Osteogenic differentiation of adipose derived stem cells promoted by overexpression of osterix. Mol Cell Biochem 301 83-92